Friday, June 19, 2009

Salmona, tuna ‘protects against age-related macular degeneration’

WASHINGTON - Omega-3 fatty acids found in fatty fish such as tuna and salmon may help prevent age-related macular degeneration (AMD) progression, depending upon the stage of the disease, suggest researchers.

AMD is a progressive disease that attacks central vision, resulting in a gradual loss of eyesight and, in some cases, blindness
During the study, the research team from Laboratory for Nutrition and Vision Research (LNVR) and Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University calculated the intakes of docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) among 2,924 patients aged 55 to 80 years.
The findings revealed that taking supplements of antioxidants plus zinc prevents progression of late-stage AMD.
"In our study, we observed participants with early stages of AMD in the placebo group benefited from higher intake of DHA, but it appears that the high-dose supplements of the antioxidants and/or the minerals somehow interfered with the benefits of DHA against early AMD progression," said senior author Dr Allen Taylor, director of the LNVR at the USDA HNRCA.
The antioxidant supplements did not seem to interfere with the protective effects of DHA and EPA against progression to advanced stages of AMD.
The study also showed that participants who consumed higher amounts of DHA and EPA appeared to have lower risk of progression to both wet and dry forms of advanced AMD.
"Data from the present study also shows the supplements and omega-3 fatty acids collaborate with low-dietary glycemic index (dGI) diets against progression to advanced AMD," said corresponding author Chung-Jung Chiu, DDS, PhD, a scientist in the LNVR and an assistant professor at TUSM.
"Our previous research suggests a low-GI diet may prevent AMD from progressing to the advanced stage," Chiu added.
The researchers suggest that eating two to three servings of fatty fish such as salmon, tuna, mackerel, shellfish, and herring every week would achieve the recommended daily intake of DHA and EPA, however, further research is required to conclude dietary recommendations for people with AMD.
The study appears in the British Journal of Ophthalmology. (ANI)


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Related?Age-Related Macular Degeneration Can Be Avoided By Taking NutrientsSeptember 15th, 2007 Researchers concluded that eating yellow and green vegetables may help people aged 60 and older avoid age-related macular degeneration, a leading cause of blindness. They have conducted a new study of some 4,500 people aged 60-80 who were screened for age-related macular degeneration, which hampers central vision. Phase-II Clinical Trial of Drug Evizon for Wet Age-Related Macular DegenerationJune 28th, 2006 Biopharmaceutical company Genaera Corporation has commenced a multi-center phase II clinical trial to explore the efficacy and safety of higher doses of its investigational drug Evizon for the treatment of the eye disease, wet age-related macular degeneration. The study is designed to evaluate up to 140 patients with wet age-related macular degeneration (AMD) treated with Evizon at four dose levels of 40mg, 80mg, 120mg and 160mg over a 20 week period. Incurable Age-Related Macular Degeneration Loom for SmokersJuly 11th, 2006 Age-related macular degeneration, which is the leading cause of irreversible visual impairment and blindness in people, aged 60 and older is another ill effect of smoking, recent study says. However it is also found that those who ate more fish rich in omega-3 fatty acids, such as mackerel, lake trout, sardines, and albacore tuna and salmon, had a lower risk of developing the vision-robbing disease. Omega-3 fatty acids, low glycemic index diet protects against age-related macular degenerationMay 3rd, 2009 WASHINGTON - Researchers from Tufts University have found that a diet rich in omega-3 fatty acids and low glycemic index food can significantly reduce the risk of age-related macular degeneration (AMD). The team led by Dr Chung-Jung Chiu, of the Laboratory for Nutrition and ision Research, and Jean Mayer USDA Human Nutrition Research Centre on Aging at Tufts University showed that nutrients, including vitamins C and E, zinc, lutein, zeaxanthin, omega-3 fatty acids (DHA and EPA), as well as low-GI foods can protect against AMD. Routine activation of immune system protein TLR3 triggers Macular degeneration August 29th, 2008 A groundbreaking discovery on macular degeneration reveals the direct association of immune system protein called TLR3 with onset of severe "dry" macular degeneration. This discovery is believed to be a breakthrough as the doctors are now in position to develop proper treatment for disease which is till now untreatable. Age Related Macular Degeneration May be Prevented with MacugenOctober 8th, 2005 Age-related macular degeneration (AMD) is the leading cause of blindness in older patients in US and the developed world. Pegaptanib sodium (Macugen) is a new treatment for exudative AMD, and has been shown to stabilize vision in approximately 70 percent of cases. Drug Quercitin in Onion Protects Against Macular Degeneration June 8th, 2008 Macular Degeneration is the major reason of blindness among the older people especially among the aged people in the USA. At least 10 million people in USA are reported to be effected by it. Hope for Age Related Macular Degeneration with LucentisDecember 31st, 2005 Genentech Inc. has applied for U.S. Salmona, tuna ‘protects against age-related macular degeneration’

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